diff --git a/src/box/vinyl.c b/src/box/vinyl.c
index 9428e934ad231ec22f9d86b76683225be76133bf..41918beba10dd5797722cf8dc212c23046db0653 100644
--- a/src/box/vinyl.c
+++ b/src/box/vinyl.c
@@ -3984,7 +3984,14 @@ vinyl_index_get(struct index *index, const char *key,
 		return -1;
 	}
 
-	if (vy_get_by_raw_key(lsm, tx, rv, key, part_count, ret) != 0)
+	/*
+	 * Make sure the LSM tree isn't deleted while we are
+	 * reading from it.
+	 */
+	vy_lsm_ref(lsm);
+	int rc = vy_get_by_raw_key(lsm, tx, rv, key, part_count, ret);
+	vy_lsm_unref(lsm);
+	if (rc != 0)
 		return -1;
 	if (*ret != NULL) {
 		tuple_bless(*ret);
diff --git a/test/vinyl/errinj_ddl.result b/test/vinyl/errinj_ddl.result
index 7bee4efdcf0a1779733181cf4d999b6cdecf90b9..dcbf90f78f43df9255afbb34616fa68d995382ce 100644
--- a/test/vinyl/errinj_ddl.result
+++ b/test/vinyl/errinj_ddl.result
@@ -894,6 +894,55 @@ s.index.secondary:select()
 s:drop()
 ---
 ...
+--
+-- gh-4109: crash if space is dropped while space.get is reading from it.
+--
+s = box.schema.space.create('test', {engine = 'vinyl'})
+---
+...
+_ = s:create_index('primary')
+---
+...
+s:replace{1}
+---
+- [1]
+...
+box.snapshot()
+---
+- ok
+...
+test_run:cmd("setopt delimiter ';'")
+---
+- true
+...
+box.error.injection.set('ERRINJ_VY_READ_PAGE_TIMEOUT', 0.01);
+---
+- ok
+...
+ch = fiber.channel(1);
+---
+...
+_ = fiber.create(function()
+    local _, ret = pcall(s.get, s, 1)
+    ch:put(ret)
+end);
+---
+...
+s:drop();
+---
+...
+ch:get();
+---
+- [1]
+...
+box.error.injection.set('ERRINJ_VY_READ_PAGE_TIMEOUT', 0);
+---
+- ok
+...
+test_run:cmd("setopt delimiter ''");
+---
+- true
+...
 box.cfg{vinyl_cache = default_vinyl_cache}
 ---
 ...
diff --git a/test/vinyl/errinj_ddl.test.lua b/test/vinyl/errinj_ddl.test.lua
index 52d9de65596edfdd931c6a745af1ccff34329ebd..6413c352ebb113a57556e18c043b739a1a5b097e 100644
--- a/test/vinyl/errinj_ddl.test.lua
+++ b/test/vinyl/errinj_ddl.test.lua
@@ -395,4 +395,24 @@ s.index.primary:select()
 s.index.secondary:select()
 s:drop()
 
+--
+-- gh-4109: crash if space is dropped while space.get is reading from it.
+--
+s = box.schema.space.create('test', {engine = 'vinyl'})
+_ = s:create_index('primary')
+s:replace{1}
+box.snapshot()
+
+test_run:cmd("setopt delimiter ';'")
+box.error.injection.set('ERRINJ_VY_READ_PAGE_TIMEOUT', 0.01);
+ch = fiber.channel(1);
+_ = fiber.create(function()
+    local _, ret = pcall(s.get, s, 1)
+    ch:put(ret)
+end);
+s:drop();
+ch:get();
+box.error.injection.set('ERRINJ_VY_READ_PAGE_TIMEOUT', 0);
+test_run:cmd("setopt delimiter ''");
+
 box.cfg{vinyl_cache = default_vinyl_cache}