diff --git a/src/box/bind.c b/src/box/bind.c
index d45a0f9a7da57b470568b434af4adfa814dd5e0d..734f6518631593e5c07ed6020d51ecf5ac04f0c9 100644
--- a/src/box/bind.c
+++ b/src/box/bind.c
@@ -191,6 +191,9 @@ sql_bind_column(struct sql_stmt *stmt, const struct sql_bind *p,
 	case MP_BIN:
 		return sql_bind_blob64(stmt, pos, (const void *) p->s, p->bytes,
 				       SQL_STATIC);
+	case MP_EXT:
+		assert(p->ext_type == MP_UUID);
+		return sql_bind_uuid(stmt, pos, &p->uuid);
 	default:
 		unreachable();
 	}
diff --git a/src/box/bind.h b/src/box/bind.h
index 568c558f38f1f74771e056f0e835f152823e0433..143f010cedfc22ca425540564975c753945fb676 100644
--- a/src/box/bind.h
+++ b/src/box/bind.h
@@ -40,6 +40,8 @@ extern "C" {
 #include <stdlib.h>
 
 #include "msgpuck.h"
+#include "uuid/tt_uuid.h"
+#include "mp_extension_types.h"
 
 struct sql_stmt;
 
@@ -59,6 +61,8 @@ struct sql_bind {
 	uint32_t bytes;
 	/** MessagePack type of the value. */
 	enum mp_type type;
+	/** Subtype of MP_EXT type. */
+	enum mp_extension_type ext_type;
 	/** Bind value. */
 	union {
 		bool b;
@@ -67,6 +71,7 @@ struct sql_bind {
 		uint64_t u64;
 		/** For string or blob. */
 		const char *s;
+		struct tt_uuid uuid;
 	};
 };
 
diff --git a/src/box/lua/execute.c b/src/box/lua/execute.c
index 1b59b2e4ac83a522956e205cf9be2400ed40bff7..62ccaf3f143f6e89f9196a54d9e1234d19d54447 100644
--- a/src/box/lua/execute.c
+++ b/src/box/lua/execute.c
@@ -371,6 +371,10 @@ lua_sql_bind_decode(struct lua_State *L, struct sql_bind *bind, int idx, int i)
 		bind->s = mp_decode_bin(&field.sval.data, &bind->bytes);
 		break;
 	case MP_EXT:
+		if (field.ext_type == MP_UUID) {
+			bind->uuid = *field.uuidval;
+			break;
+		}
 		diag_set(ClientError, ER_SQL_BIND_TYPE, "USERDATA",
 			 sql_bind_name(bind));
 		return -1;
@@ -386,6 +390,7 @@ lua_sql_bind_decode(struct lua_State *L, struct sql_bind *bind, int idx, int i)
 		unreachable();
 	}
 	bind->type = field.type;
+	bind->ext_type = field.ext_type;
 	lua_pop(L, lua_gettop(L) - idx);
 	return 0;
 }
diff --git a/src/box/sql/sqlInt.h b/src/box/sql/sqlInt.h
index ef8dcd693d9fdaf231d35cca72d4044ef5db19e4..115c52f96b7f307a6069a621c3952fa51d54ec40 100644
--- a/src/box/sql/sqlInt.h
+++ b/src/box/sql/sqlInt.h
@@ -326,6 +326,8 @@ struct sql_vfs {
 #define SQL_LIMIT_LIKE_PATTERN_LENGTH       8
 #define SQL_LIMIT_TRIGGER_DEPTH             9
 
+struct tt_uuid;
+
 enum sql_ret_code {
 	/** sql_step() has another row ready. */
 	SQL_ROW = 1,
@@ -634,6 +636,9 @@ int
 sql_bind_zeroblob64(sql_stmt *, int,
 			sql_uint64);
 
+int
+sql_bind_uuid(struct sql_stmt *stmt, int i, const struct tt_uuid *uuid);
+
 /**
  * Return the number of wildcards that should be bound to.
  */
diff --git a/src/box/sql/vdbeapi.c b/src/box/sql/vdbeapi.c
index aaae12e415903268d5c87314ff6e466f38e404b8..8031ee0dc1071a9b6133c48247910200b8435969 100644
--- a/src/box/sql/vdbeapi.c
+++ b/src/box/sql/vdbeapi.c
@@ -840,6 +840,16 @@ sql_bind_zeroblob64(sql_stmt * pStmt, int i, sql_uint64 n)
 	return sql_bind_zeroblob(pStmt, i, n);
 }
 
+int
+sql_bind_uuid(struct sql_stmt *stmt, int i, const struct tt_uuid *uuid)
+{
+	struct Vdbe *p = (struct Vdbe *)stmt;
+	if (vdbeUnbind(p, i) != 0 || sql_bind_type(p, i, "uuid") != 0)
+		return -1;
+	mem_set_uuid(&p->aVar[i - 1], uuid);
+	return 0;
+}
+
 int
 sql_bind_parameter_count(const struct sql_stmt *stmt)
 {
diff --git a/test/sql-tap/gh-6164-uuid-follow-ups.test.lua b/test/sql-tap/gh-6164-uuid-follow-ups.test.lua
index a8f662f77301b58b831a32cc4af3c99741b33a8a..4fc5052d85e0de8aa31fa52aa36b0fe631492add 100755
--- a/test/sql-tap/gh-6164-uuid-follow-ups.test.lua
+++ b/test/sql-tap/gh-6164-uuid-follow-ups.test.lua
@@ -1,6 +1,6 @@
 #!/usr/bin/env tarantool
 local test = require("sqltester")
-test:plan(1)
+test:plan(4)
 
 -- Make sure that function quote() can work with uuid.
 test:do_execsql_test(
@@ -11,4 +11,28 @@ test:do_execsql_test(
         '11111111-1111-1111-1111-111111111111'
     })
 
+-- Make sure that uuid value can be binded.
+local uuid1 = require('uuid').fromstr('11111111-1111-1111-1111-111111111111')
+local uuid2 = require('uuid').fromstr('11111111-2222-1111-1111-111111111111')
+local uuid3 = require('uuid').fromstr('11111111-1111-3333-1111-111111111111')
+test:do_test(
+    "gh-6164-2",
+    function()
+        return box.execute([[SELECT ?;]], {uuid1}).rows[1][1]
+    end,
+    uuid1)
+test:do_test(
+    "gh-6164-3",
+    function()
+        return box.execute([[SELECT $2;]], {123, uuid2}).rows[1][1]
+    end,
+    uuid2)
+
+test:do_test(
+    "gh-6164-4",
+    function()
+        return box.execute([[SELECT :two;]], {{[":two"] = uuid3}}).rows[1][1]
+    end,
+    uuid3)
+
 test:finish_test()